BDBM24626 6-chloropyrazin-2-amine::6-chloropyrazin-2-amine, 5::CHEMBL191632

SMILES c1c(nc(cn1)Cl)N

InChI Key InChIKey=JTPXVCKCLBROOJ-UHFFFAOYSA-N

Data  1 IC50  1 Other

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24626   

LigandPNGBDBM24626(CHEMBL191632 | 6-chloropyrazin-2-amine | 6-chlorop...)
Affinity DatapH: 7.2 T: 2°CAssay Description:CDK2/cyclin A activity was determined using a radiometric assay to measure the incorporation of gamma-phosphate from [gamma-33P]-ATP into histone H1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM24626(CHEMBL191632 | 6-chloropyrazin-2-amine | 6-chlorop...)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)