BDBM24243 2-amino-N-[4-(benzyloxy)phenyl]acetamide::Amino acid analog, 2::CHEMBL479960

SMILES c1ccc(cc1)COc2ccc(cc2)NC(=O)CN

InChI Key InChIKey=YJPUATSIKWOSST-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24243   

TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

LigandPNGBDBM24243(CHEMBL479960 | 2-amino-N-[4-(benzyloxy)phenyl]acet...)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

LigandPNGBDBM24243(CHEMBL479960 | 2-amino-N-[4-(benzyloxy)phenyl]acet...)
Affinity DataIC50: 300nMAssay Description:Inhibition of LTA4 hydrolase by hydrolase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

LigandPNGBDBM24243(CHEMBL479960 | 2-amino-N-[4-(benzyloxy)phenyl]acet...)
Affinity DataIC50: 135nMAssay Description:Inhibition of LTA4 hydrolase by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)