BDBM24174 3-N,3-N-diethyl-5,5-dimethyl-2-N-(thiophene-2-)-4,5,6,7-tetrahydro-1-benzothiophene-2,3-diamido::thiophene containing compound, 37

SMILES CCN(CC)C(=O)c1c2c(sc1NC(=O)c3cccs3)CCC(C2)(C)C

InChI Key InChIKey=BCQPPORYBRTCLZ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24174   

TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandPNGBDBM24174(3-N,3-N-diethyl-5,5-dimethyl-2-N-(thiophene-2-)-4,...)
Affinity DataIC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:KSP ATPase activity was determined by measuring production of ADP (ADPQuest Assay, DiscoverX). Raw fluorescence data were normalized to negative (DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Kalypsys

LigandPNGBDBM24174(3-N,3-N-diethyl-5,5-dimethyl-2-N-(thiophene-2-)-4,...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)