BDBM234853 US9353116, 11

SMILES CCS(=O)(=O)Nc1cccc(c1)Cc2c3c(ncnc3n(n2)C(C)C)N

InChI Key InChIKey=CZDNNNYBOADUFI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234853   

TargetProto-oncogene tyrosine-protein kinase Src [251-533](Chicken)
University of California

US Patent
LigandPNGBDBM234853(US9353116, 11)
Affinity DataIC50: 5.00E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src [251-533,T338C](Chicken)
University of California

US Patent
LigandPNGBDBM234853(US9353116, 11)
Affinity DataIC50: 3.50E+3nMpH: 8.0Assay Description:In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)