BDBM231628 IDI-6253

SMILES Cc1nnc2n1nc(c3c2cccc3)N4CCc5ccccc5C4

InChI Key InChIKey=NMJYSGXBNVGFPT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231628   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Harvard School of Public Health

LigandPNGBDBM231628(IDI-6253)
Affinity DataIC50: 3.50E+3nMAssay Description:Substrate-dependent inhibition of recombinant PfDHODH protein was assessed in an in vitro assay in 384-well clear plates (Corning 3702) as described ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Harvard School of Public Health

LigandPNGBDBM231628(IDI-6253)
Affinity DataIC50: 3.80E+3nMAssay Description:Substrate-dependent inhibition of recombinant PfDHODH protein was assessed in an in vitro assay in 384-well clear plates (Corning 3702) as described ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed