BDBM229646 BDBM229674::US9334269, J

SMILES Cc1cc(ccc1OC2CN(C2)c3ccnc(n3)Nc4cccc(c4)C(=O)NC)F

InChI Key InChIKey=MFAKJGXMORSMIX-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 229646   

LigandPNGBDBM229646(BDBM229674 | US9334269, J)
Affinity DataIC50: 80nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM229646(BDBM229674 | US9334269, J)
Affinity DataIC50: 80nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)