BDBM210871 US9290467, 41

SMILES c1cc2c(cc1C[C@H](NC(=O)c3cc(ccc3OC/C=C/CO2)C4CNC4)C(=O)NC5(CC5)C#N)Cl

InChI Key InChIKey=GIZLJBNLBSDHDB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210871   

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent

LigandBDBM210871(US9290467, 41)Copy SMILESCopy InChI

Affinity DataIC50: 5.20nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
1/30/2017
Entry Details
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PDB3D Structure (crystal)
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