BDBM209397 US9266890, I-6

SMILES CN1c2cnc(nc2N(CCC1=O)C3CCCC3)Nc4ccc(cc4OC)N5CCC(CC5)O

InChI Key InChIKey=KBILTEUAXWLXKP-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209397   

TargetDual specificity protein kinase TTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM209397(US9266890, I-6)
Affinity DataIC50: 342nMT: 2°CAssay Description:Kinase reactions were carried out at room temperature with the following components: 1× kinase reaction buffer, 5 μg/mL (40 nM) Mps1 kinase, 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM209397(US9266890, I-6)
Affinity DataKd:  19nMAssay Description:In vitro Plk1 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent