BDBM20156 1-benzyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987::Substituted Maleimide, 4

SMILES COc1ccc(cc1)NC2=C(C(=O)N(C2=O)Cc3ccccc3)c4ccccc4

InChI Key InChIKey=HLZMYWLMBBLASX-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20156   

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

LigandPNGBDBM20156(Substituted Maleimide, 4 | 1-benzyl-3-[(4-methoxyp...)
Affinity DataEC50:  50nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

LigandPNGBDBM20156(Substituted Maleimide, 4 | 1-benzyl-3-[(4-methoxyp...)
Affinity DataEC50:  40nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed