BDBM17714 5,6-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-d]pyrimidin-4-amine::5,6-diphenylfuro[2,3-d]pyrimidin-4-amine, 1::CHEMBL247272

SMILES C(CN1CCNCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1

InChI Key InChIKey=PTILEOLOGGMFCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17714   

LigandPNGBDBM17714(CHEMBL247272 | 5,6-diphenyl-N-[2-(piperazin-1-yl)e...)
Affinity DataIC50: 2.60E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17714(CHEMBL247272 | 5,6-diphenyl-N-[2-(piperazin-1-yl)e...)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17714(CHEMBL247272 | 5,6-diphenyl-N-[2-(piperazin-1-yl)e...)
Affinity DataIC50: 81nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM17714(CHEMBL247272 | 5,6-diphenyl-N-[2-(piperazin-1-yl)e...)
Affinity DataIC50: 181nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed