BDBM17664 (2S)-2-amino-3-(phosphonooxy)propanoic acid::CHEMBL284377::L-SOP::L-serine O-phosphate

SMILES N[C@@H](COP(O)(O)=O)C(O)=O

InChI Key InChIKey=BZQFBWGGLXLEPQ-UHFFFAOYSA-N

Data  5 KI  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 17664   

LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataIC50: 5.23E+5nMpH: 7.4 T: 2°CAssay Description:The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2007
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataEC50:  2.70E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataEC50:  1.30E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataEC50:  1.60E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataEC50:  4.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Cns Research

Curated by ChEMBL
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataKi:  2.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664(CHEMBL284377 | L-serine O-phosphate | (2S)-2-amino...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed