BindingDB BDBM174948 US9096593, P-2049

BDBM174948 US9096593, P-2049

SMILES Cc1cc2c(c[nH]c2nc1)Cc3ccc(nc3F)NCc4cc(cnc4OC)F

InChI Key InChIKey=NSMOZFXKTHCPTQ-UHFFFAOYSA-N

Data 215 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 215 hits for monomerid = 174948

Macrophage colony-stimulating factor 1 receptor(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent
PDB

3D Structure (crystal)

Mast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 100nMpH: 7.5Assay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Cytochrome P450 1A2(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Cytochrome P450 2C19(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Cytochrome P450 2C9(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Cytochrome P450 2D6(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Cytochrome P450 3A4(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

PDB KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Cytochrome P450 3A4(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

PDB KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
4/11/2016
Entry Details
Go to US Patent

Macrophage colony-stimulating factor 1 receptor(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 26nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Macrophage colony-stimulating factor 1 receptor(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 16nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed PDB

3D Structure (crystal)

Macrophage colony-stimulating factor 1 receptor(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 16nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed PDB

3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 390nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Mast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent

BDBM174948(US9096593, P-2049)

IC50: 860nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Aurora kinase C(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Vascular endothelial growth factor receptor 2(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.10E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Tyrosine-protein kinase ABL1(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Tyrosine-protein kinase ABL2(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Activin receptor type-1B(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Beta-adrenergic receptor kinase 1(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Beta-adrenergic receptor kinase 2(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

RAC-alpha serine/threonine-protein kinase(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

RAC-beta serine/threonine-protein kinase(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

RAC-gamma serine/threonine-protein kinase(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

ALK tyrosine kinase receptor(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Aurora kinase A(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Aurora kinase B(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Tyrosine-protein kinase receptor UFO(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Tyrosine-protein kinase Blk(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Cytoplasmic tyrosine-protein kinase BMX(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Serine/threonine-protein kinase BRSK1(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Tyrosine-protein kinase BTK(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Calcium/calmodulin-dependent protein kinase type 1(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Calcium/calmodulin-dependent protein kinase type 1D(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit alpha(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit beta(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Calcium/calmodulin-dependent protein kinase type II subunit delta(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Calcium/calmodulin-dependent protein kinase type IV(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Serine/threonine-protein kinase MRCK alpha(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Serine/threonine-protein kinase MRCK beta(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Platelet-derived growth factor receptor alpha/beta(Mouse)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Serine/threonine-protein kinase Chk1(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Inhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Dual specificity protein kinase CLK2(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Tyrosine-protein kinase CSK(Human)
University of California Irvine (UCI)

Curated by ChEMBL

BDBM174948(US9096593, P-2049)

IC50: 1.00E+3nMMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid PDB Similars

Date in BDB:
10/13/2025
Entry Details
PubMed

Displayed 1 to 50 (of 215 total ) | Next | Last >>

Filter my 215 hits

Targets 189▿
- Platelet-derived growth factor receptor alpha/beta 9
- Macrophage colony-stimulating factor 1 receptor 8
- Receptor-type tyrosine-protein kinase FLT3 4
- Mast/stem cell growth factor receptor Kit 4
- Proto-oncogene tyrosine-protein kinase receptor Ret 3
- Protein kinase C beta type 2
- Tyrosine-protein kinase Lyn 2
- Cytochrome P450 3A4 2
- Receptor tyrosine-protein kinase erbB-4 1
- Receptor tyrosine-protein kinase erbB-2 1
- Tyrosine-protein kinase FRK 1
- Hepatocyte growth factor receptor 1
- ALK tyrosine kinase receptor 1
- Serine/threonine-protein kinase Nek9 1
- Glycogen synthase kinase-3 alpha 1
- Glycogen synthase kinase-3 beta 1
- Serine/threonine-protein kinase Nek6 1
- Calcium/calmodulin-dependent protein kinase type 1 1
- Protein kinase C iota type 1
- Calcium/calmodulin-dependent protein kinase type II subunit beta 1
- Serine/threonine-protein kinase Nek2 1
- Serine/threonine-protein kinase Nek1 1
- Macrophage-stimulating protein receptor 1
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 1
- Sphingosine kinase 1 1
- MAP/microtubule affinity-regulating kinase 3 1
- Homeodomain-interacting protein kinase 4 1
- Protein kinase C theta type 1
- Serine/threonine-protein kinase PAK 2 1
- Serine/threonine-protein kinase PAK 3 1
- Serine/threonine-protein kinase PAK 4 1
- Serine/threonine-protein kinase PAK 5 1
- Serine/threonine-protein kinase PAK 6 1
- Tyrosine-protein kinase JAK3 1
- Tyrosine-protein kinase JAK2 1
- MAP/microtubule affinity-regulating kinase 4 1
- Tyrosine-protein kinase ZAP-70 1
- Leucine-rich repeat serine/threonine-protein kinase 2 1
- Serine/threonine-protein kinase Sgk2 1
- Serine/threonine-protein kinase Sgk1 1
- Casein kinase I isoform gamma-3 1
- Casein kinase I isoform gamma-2 1
- Serine/threonine-protein kinase Sgk3 1
- Casein kinase I isoform epsilon 1
- Casein kinase I isoform gamma-1 1
- Ephrin type-A receptor 1 1
- Ephrin type-A receptor 3 1
- Ephrin type-A receptor 2 1
- Ephrin type-A receptor 5 1
- Tyrosine-protein kinase BTK 1
- Serine/threonine-protein kinase mTOR 1
- Tyrosine-protein kinase ITK/TSK 1
- Tyrosine-protein kinase receptor UFO 1
- Protein kinase C eta type 1
- Insulin-like growth factor 1 receptor 1
- Tyrosine-protein kinase Blk 1
- Epidermal growth factor receptor 1
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1
- Homeodomain-interacting protein kinase 2 1
- Cytochrome P450 1A2 1
- Homeodomain-interacting protein kinase 1 1
- Ribosomal protein S6 kinase beta-1 1
- Cytochrome P450 2C9 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3 1
- Casein kinase I isoform delta 1
- Serine/threonine-protein kinase 25 1
- Ephrin type-B receptor 3 1
- Ephrin type-B receptor 4 1
- Ephrin type-B receptor 1 1
- Ephrin type-B receptor 2 1
- Rhodopsin kinase GRK7 1
- MAP kinase-activated protein kinase 2 1
- MAP kinase-activated protein kinase 3 1
- Platelet-derived growth factor receptor beta 1
- Ephrin type-A receptor 8 1
- MAP kinase-activated protein kinase 5 1
- Cytochrome P450 2D6 1
- Phosphatidylinositol 4-kinase beta 1
- Death-associated protein kinase 1 1
- Tyrosine-protein kinase Fer 1
- Serine/threonine-protein kinase D2 1
- Serine/threonine-protein kinase D3 1
- Serine/threonine-protein kinase D1 1
- Calcium/calmodulin-dependent protein kinase type II subunit delta 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1
- Death-associated protein kinase 3 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1
- Beta-adrenergic receptor kinase 2 1
- Beta-adrenergic receptor kinase 1 1
- Serine/threonine-protein kinase pim-1 1
- Serine/threonine-protein kinase pim-2 1
- Testis-specific serine/threonine-protein kinase 1 1
- Angiopoietin-1 receptor 1
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Protein kinase C epsilon type 1
- Testis-specific serine/threonine-protein kinase 2 1
- Serine/threonine-protein kinase MRCK alpha 1
- Mitogen-activated protein kinase kinase kinase kinase 4 1
- Mitogen-activated protein kinase kinase kinase kinase 5 1
- Activin receptor type-1B 1
- Casein kinase II subunit alpha 1
- Leukocyte tyrosine kinase receptor 1
- Interleukin-1 receptor-associated kinase 4 1
- Cytoplasmic tyrosine-protein kinase BMX 1
- RAC-gamma serine/threonine-protein kinase 1
- Tyrosine-protein kinase ABL2 1
- Tyrosine-protein kinase ABL1 1
- RAC-alpha serine/threonine-protein kinase 1
- Calcium/calmodulin-dependent protein kinase type II subunit alpha 1
- Megakaryocyte-associated tyrosine-protein kinase 1
- cGMP-dependent protein kinase 2 1
- Rho-associated protein kinase 2 1
- cGMP-dependent protein kinase 1 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1
- Rho-associated protein kinase 1 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Tyrosine-protein kinase Fes/Fps 1
- Serine/threonine-protein kinase SIK2 1
- BDNF/NT-3 growth factors receptor 1
- Mitogen-activated protein kinase 1 1
- Tyrosine-protein kinase Lck 1
- Mitogen-activated protein kinase 3 1
- Serine/threonine-protein kinase 4 1
- Protein kinase C delta type 1
- NT-3 growth factor receptor 1
- G protein-coupled receptor kinase 5 1
- SRSF protein kinase 2 1
- G protein-coupled receptor kinase 4 1
- Dual specificity protein kinase CLK2 1
- Protein-tyrosine kinase 2-beta 1
- Tyrosine-protein kinase Mer 1
- G protein-coupled receptor kinase 6 1
- Calcium/calmodulin-dependent protein kinase type IV 1
- Serine/threonine-protein kinase N1 1
- Ribosomal protein S6 kinase alpha-2 1
- Tyrosine-protein kinase SYK 1
- Ribosomal protein S6 kinase alpha-3 1
- Ribosomal protein S6 kinase alpha-1 1
- Serine/threonine-protein kinase TBK1 1
- SRC kinase signaling inhibitor 1 1
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 1
- Calcium/calmodulin-dependent protein kinase type 1D 1
- Fibroblast growth factor receptor 4 1
- Aurora kinase B 1
- Vascular endothelial growth factor receptor 2 1
- Tyrosine-protein kinase Fgr 1
- Insulin receptor 1
- Vascular endothelial growth factor receptor 3 1
- Tyrosine-protein kinase HCK 1
- Aurora kinase A 1
- Fibroblast growth factor receptor 1 1
- Fibroblast growth factor receptor 2 1
- Aurora kinase C 1
- Fibroblast growth factor receptor 3 1
- Serine/threonine-protein kinase PLK1 1
- Serine/threonine-protein kinase PLK2 1
- Inhibitor of nuclear factor kappa-B kinase subunit beta 1
- Serine/threonine-protein kinase PLK3 1
- Mitogen-activated protein kinase 13 1
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 1
- Mitogen-activated protein kinase 12 1
- Tyrosine-protein kinase receptor TYRO3 1
- RAC-beta serine/threonine-protein kinase 1
- Serine/threonine-protein kinase BRSK1 1
- Casein kinase I isoform alpha 1
- Protein kinase C gamma type 1
- Misshapen-like kinase 1 1
- Tyrosine-protein kinase Fyn 1
- Tyrosine-protein kinase CSK 1
- cAMP-dependent protein kinase catalytic subunit alpha 1
- Ribosomal protein S6 kinase alpha-6 1
- Protein kinase C alpha type 1
- Ribosomal protein S6 kinase alpha-4 1
- Platelet-derived growth factor receptor alpha 1
- Ribosomal protein S6 kinase alpha-5 1
- Maternal embryonic leucine zipper kinase 1
- Eukaryotic elongation factor 2 kinase 1
- Protein kinase C zeta type 1
- Serine/threonine-protein kinase MARK1 1
- Serine/threonine-protein kinase MARK2 1
- Serine/threonine-protein kinase Chk1 1
- cAMP-dependent protein kinase catalytic subunit PRKX 1
- SRSF protein kinase 1 1
- Tyrosine-protein kinase Yes 1
- Serine/threonine-protein kinase MRCK beta 1
- Cytochrome P450 2C19 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 4 1
- Casein kinase II subunit alpha' 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 3 1
- ...
Publications 3▿
- Nat Commun 10: 205
- US Patent US9096593 (2015) 8
- Eur J Med Chem 245: 2
Institutions 3▿
- University of California Irvine (UCI) 205
- Plexxikon 8
- Shenyang Pharmaceutical University 2
Affinity: 16 to 1.0E+4 nM▿
- IC50 215
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1