BDBM16661 1-N-(4-fluorobenzene)benzene-1,4-disulfonamide::aromatic sulfonamide compound 26

SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=USGGSIVMQBZIHX-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 16661   

TargetIntestinal-type alkaline phosphatase(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataIC50: 100nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataKi:  9nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi Di Firenze

LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataKi:  15nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mouse)
Universita Degli Studi Di Firenze

LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataKi:  20nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataKi:  40nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed