BDBM16429 2,6-Dichlorophenylacetic acid::2-(2,6-dichlorophenyl)acetic acid::CHEMBL240293::EINECS 229-504-0

SMILES c1cc(c(c(c1)Cl)CC(=O)O)Cl

InChI Key InChIKey=SFAILOOQFZNOAU-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16429   

TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Human)
Medical College of Wiscosin

LigandPNGBDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataKi:  1.00E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataKi:  4.40E+3nM ΔG°:  -7.30kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)