BDBM15922 2-pyridinecarboxamide deriv. 17b::5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide

SMILES CCOc1c(ccc(n1)C(=O)NCc2cc(ccc2OC)OC)C#N

InChI Key InChIKey=VEGKZYFYGCWXMN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15922   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15922(5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypy...)
Affinity DataIC50: 230nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)