BDBM152235 US8993552, 70

SMILES CCCc1cc2c(ncnc2s1)N3CCN(CC3)C4=NCC(S4)(C)C

InChI Key InChIKey=SRQYLNYQAPCPIR-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 152235   

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM152235(US8993552, 70)
Affinity DataIC50: 430nMAssay Description:NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM152235(US8993552, 70)
Affinity DataKd:  158nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM152235(US8993552, 70)
Affinity DataIC50: 446nMAssay Description:Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)