BDBM15019 CHEMBL385178::N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::nicotinamide 35

SMILES c1ccc(cc1)Oc2ccc(cc2)NC(=O)c3cccnc3NCc4ccncc4

InChI Key InChIKey=CPVRYQAOUPSUDO-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15019   

TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM15019(N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]p...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
LigandPNGBDBM15019(N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]p...)
Affinity DataIC50: 38nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM15019(N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]p...)
Affinity DataKi:  10nMAssay Description:Inhibition of phosphorylated-Kdr after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)