BDBM14321 Fragment 18::quinolin-4-ol

SMILES c1ccc2c(c1)c(ccn2)O

InChI Key InChIKey=PMZDQRJGMBOQBF-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14321   

TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM14321(quinolin-4-ol | Fragment 18)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Celera

LigandPNGBDBM14321(quinolin-4-ol | Fragment 18)
Affinity DataKi: >2.00E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14321(quinolin-4-ol | Fragment 18)
Affinity DataKi: >2.00E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed