BDBM14312 CHEMBL214368::CRA23::ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylcarbamoyl)phenyl]methyl}-1,2,4-oxadiazol-3-yl)-1-oxohexan-2-yl]carbamate

SMILES CCOC(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(cc2)C(=O)NC2Cc3ccccc3C2)n1

InChI Key InChIKey=PWHBUXLKTXHYAP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14312   

TargetDimer of Tryptase beta-2(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM14312(ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-ind...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Celera

LigandPNGBDBM14312(ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-ind...)
Affinity DataKi:  3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14312(ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-ind...)
Affinity DataKi:  170nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM14312(ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-ind...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM14312(ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-ind...)
Affinity DataKi: >1.50E+5nMAssay Description:Inhibition of F7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM14312(ethyl N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-ind...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed