BDBM138203 US8871778, 160

SMILES Cc1nn(cc1CN1CC(O)C1)-c1ccnc(Nc2ccc3n(C)ncc3c2)n1

InChI Key InChIKey=FFTGDASJRVPWKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 138203   

TargetTyrosine-protein kinase SYK(Human)
Genosco

US Patent
LigandPNGBDBM138203(US8871778, 160)
Affinity DataIC50: 15.2nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Genosco

US Patent
LigandPNGBDBM138203(US8871778, 160)
Affinity DataIC50: 1.87E+3nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK(Human)
Genosco

US Patent
LigandPNGBDBM138203(US8871778, 160)
Affinity DataIC50: 20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed