BDBM13738 5-methyl-5-(propan-2-yl)-2-{[2-(trifluoromethyl)phenyl]amino}-4,5-dihydro-1,3-thiazol-4-one::racemic::thiazolone analog 1

SMILES CC(C)C1(C)SC(Nc2ccccc2C(F)(F)F)=NC1=O

InChI Key InChIKey=BNGZBGRFUCBRBU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13738   

LigandPNGBDBM13738(5-methyl-5-(propan-2-yl)-2-{[2-(trifluoromethyl)ph...)
Affinity DataKi:  503nM ΔG°:  -8.50kcal/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed