BDBM13664 3-Oxybenzamide 50::3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxy-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzamide

SMILES COc1ccc(cc1OCCc2ccc(cc2Cl)Cl)C(=O)NCC3CCN(CC3)c4ccncc4

InChI Key InChIKey=UVSAHJWEJXWVGO-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13664   

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13664(3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxy-N-{[1-(...)
Affinity DataKi:  18nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13664(3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxy-N-{[1-(...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13664(3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxy-N-{[1-(...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13664(3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxy-N-{[1-(...)
Affinity DataKi:  2.71E+3nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed