BDBM12582 1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole::1-(4-chlorophenyl)-1H-tetrazole::CHEMBL440394::US11634391, Compound 216::chlorophenyl-tetrazole compound 1

SMILES Clc1ccc(cc1)-n1cnnn1

InChI Key InChIKey=FVXFXVKZUVWQGE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12582   

TargetProthrombin(Human)
Astex

LigandPNGBDBM12582(CHEMBL440394 | 1-(4-chlorophenyl)-1H-1,2,3,4-tetra...)
Affinity DataIC50: 3.30E+5nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetProthrombin(Human)
Astex

LigandPNGBDBM12582(CHEMBL440394 | 1-(4-chlorophenyl)-1H-1,2,3,4-tetra...)
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Astex

LigandPNGBDBM12582(CHEMBL440394 | 1-(4-chlorophenyl)-1H-1,2,3,4-tetra...)
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM12582(CHEMBL440394 | 1-(4-chlorophenyl)-1H-1,2,3,4-tetra...)
Affinity DataIC50: 2.69E+4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent