BDBM124200 US8748458, 4

SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccc2ccccc2n1

InChI Key InChIKey=JMWOJCWEYBYEOY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 124200   

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 71nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 212nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 62nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 545nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 5(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 123nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 16nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 7(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 157nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 312nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 90nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 126nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 11(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50: 112nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent