BDBM124199 US8748458, 3

SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1

InChI Key InChIKey=QKTORDWLHYWRJF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 124199   

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 458nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 1.54E+3nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 710nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 307nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 5(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 458nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124199(US8748458, 3)
Affinity DataIC50: 9nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent