BDBM12398 1-(3-Methoxy-benzyl)-1H-indole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide::1-[(3-methoxyphenyl)methyl]-N-[1-(propan-2-yl)piperidin-4-yl]-1H-indole-2-carboxamide::2-Carboxyindole Scaffold 43::2-carboxyindole 12

SMILES CC(C)N1CCC(CC1)NC(=O)c2cc3ccccc3n2Cc4cccc(c4)OC

InChI Key InChIKey=GIPCBGDQVGKMPO-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12398   

TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12398(1-[(3-methoxyphenyl)methyl]-N-[1-(propan-2-yl)pipe...)
Affinity DataKi:  89nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM12398(1-[(3-methoxyphenyl)methyl]-N-[1-(propan-2-yl)pipe...)
Affinity DataKi:  89nM ΔG°:  -9.61kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)