BDBM123786 AAP1742

SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1

InChI Key InChIKey=RZLCSJZALMLKCU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 123786   

TargetCyclin-dependent kinase 1(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.33E+3nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 549nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 454nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.49E+4nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Institute of Experimental Botany Ascr and Palacky University

LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 280nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 550nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 450nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palack�

Curated by ChEMBL
LigandPNGBDBM123786(AAP1742)
Affinity DataIC50: 280nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed