BDBM12027 3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol::4-Arylazo-3,5-diamino-1H-pyrazole 30b

SMILES Nc1n[nH]c(N)c1\N=N\c1cccc(O)c1

InChI Key InChIKey=WELGNMVJTNYIRH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 12027   

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 5.10E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 5.60E+4nMpH: 7.2 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 8.20E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12027(3-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed