BDBM119439 BDBM119694::US8685986, 13

SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(O)cc2)-c2cccs2)cc1

InChI Key InChIKey=LFEKORZSWOREFY-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 119439   

TargetHistone deacetylase 1(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119439(US8685986, 13 | BDBM119694)
Affinity DataIC50: 865nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119439(US8685986, 13 | BDBM119694)
Affinity DataIC50: 1.91E+3nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119439(US8685986, 13 | BDBM119694)
Affinity DataIC50: 614nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119439(US8685986, 13 | BDBM119694)
Affinity DataIC50: 6.60nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119439(US8685986, 13 | BDBM119694)
Affinity DataIC50: 559nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Ube Industries

US Patent
LigandPNGBDBM119439(US8685986, 13 | BDBM119694)
Affinity DataKi:  13nM ΔG°:  -10.9kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
Go to US Patent