BDBM11850 2-[(4-methoxybenzene)sulfonamido]-3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]ethyl}propanamide::5-mercapto-1,3,4-thiadiazole 12p

SMILES COc1ccc(cc1)S(=O)(=O)NC(Cc1ccccc1)C(=O)NC(C)C(=O)Nc1nnc(S)s1

InChI Key InChIKey=CLSZSRWILIUAGI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 11850   

TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi Di Firenze

LigandPNGBDBM11850(2-[(4-methoxybenzene)sulfonamido]-3-phenyl-N-{1-[(...)
Affinity DataKi:  1.40E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11850(2-[(4-methoxybenzene)sulfonamido]-3-phenyl-N-{1-[(...)
Affinity DataKi:  1.80E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11850(2-[(4-methoxybenzene)sulfonamido]-3-phenyl-N-{1-[(...)
Affinity DataKi:  2.00E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11850(2-[(4-methoxybenzene)sulfonamido]-3-phenyl-N-{1-[(...)
Affinity DataKi:  2.10E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11850(2-[(4-methoxybenzene)sulfonamido]-3-phenyl-N-{1-[(...)
Affinity DataKi:  2.80E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed