BDBM11386 Hydroxysulfonamide 67::N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)NO

InChI Key InChIKey=RRPKGUUYTHFUPN-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11386   

TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  62nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  156nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  2.10E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  3.40E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  3.60E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  3.90E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  4.00E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11386(N-hydroxy-2,4,6-trimethylbenzene-1-sulfonamide | H...)
Affinity DataKi:  7.20E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed