BDBM11385 Hydroxysulfonamide 66::N-hydroxy-4-methoxybenzene-1-sulfonamide

SMILES COc1ccc(cc1)S(=O)(=O)NO

InChI Key InChIKey=MBKXTRZDNQFIJG-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11385   

TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  51nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  110nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  1.20E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  1.40E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  1.60E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  2.00E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  3.30E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11385(N-hydroxy-4-methoxybenzene-1-sulfonamide | Hydroxy...)
Affinity DataKi:  6.80E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed