BDBM113590 US8633196, 21::US9365529, 21

SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1

InChI Key InChIKey=OEKBBQNVZPGHFU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 113590   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 63nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 63nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetInterstitial collagenase(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 1.17E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetStromelysin-1(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 887nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 9(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113590(US8633196, 21 | US9365529, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent