BDBM113589 US8633196, 19::US9365529, 19

SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key InChIKey=UFNKXVJYCDHZQW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 113589   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetInterstitial collagenase(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 2.30E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetStromelysin-1(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 1.77E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 9(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 3.05E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Galderma Research & Devlopment

US Patent
LigandPNGBDBM113589(US8633196, 19 | US9365529, 19)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent