BDBM11332 Hydroxamate 13::N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfonamido]propanamide::N-n-Perfluorobutylsulfonyl-alanine hydroxamate

SMILES CC(NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)NO

InChI Key InChIKey=CSAFQHHGNGUQOL-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 11332   

TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  16nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  17nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  21nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  69nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  69nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  79nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  118nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  120nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi:  121nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11332(N-hydroxy-2-[(1,1,2,2,3,3,4,4,4-nonafluorobutane)s...)
Affinity DataKi: >200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed