BDBM112625 GNE-643

SMILES c1cc(ccc1CNC(=O)c2ccn3ccnc3c2)S(=O)(=O)c4cc(cc(c4)F)F

InChI Key InChIKey=YECCIJSXGJHBSG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112625   

LigandPNGBDBM112625(GNE-643)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The reaction was carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well plates. NAMPT protein was added to 1 B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)