BDBM11031 2-propyl-N-(5-sulfamoyl-2,3-dihydro-1H-inden-2-yl)pentanamide::2-valproylamido-5-sulfonamidoindane::CHEMBL381730::Indanesulfonamide Derivative 12a

SMILES CCCC(CCC)C(=O)N[C@@H]1Cc2ccc(cc2C1)S(=O)(=O)N

InChI Key InChIKey=XBYJCVDSFWJBSM-UHFFFAOYSA-N

Data  6 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11031   

TargetCarbonic anhydrase 2(Human)
University of Namur

LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  0.900nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  9.30nMAssay Description:Inhibition of human carbonic anhydrase 7 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  28nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Namur

LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  282nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  658nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Namur

LigandPNGBDBM11031(2-valproylamido-5-sulfonamidoindane | CHEMBL381730...)
Affinity DataKi:  4.13E+3nM ΔG°:  -7.27kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed