BDBM10882 6-ethoxy-1,3-benzothiazole-2-sulfonamide::CHEMBL18::Ethamide::Ethoxazolamide::Ethoxzolamide::Ethoxzolamide (EZA)::Ethoxzolamide, EZM::Sulfonamide, 3::US10172837, Ethoxyzolamide::sulfonamide 3

SMILES CCOc1ccc2c(c1)sc(n2)S(=O)(=O)N

InChI Key InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N

Data  378 KI  4 IC50  16 Kd

PDB links: 9 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 398 hits for monomerid = 10882   

TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  14nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  0.710nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  0.710nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  36nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  13nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of GST-tagged recombinant carbonic anhydrase-9 catalytic domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full length carbonic anhydrase-2 in human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length carbonic anhydrase-1 in human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  13nMpH: 7.0Assay Description:Binding affinity to human recombinant CA13 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  36nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  0.710nMpH: 7.0Assay Description:Binding affinity to human recombinant CA7 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  1.10nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  14nMpH: 7.0Assay Description:Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataIC50: 8nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  14nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  13nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Vilnius University

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  33nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 6 expressed in Escherichia coli Rosetta2 (DE3) by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  36nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 12 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  0.710nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  0.710nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.490nMAssay Description:In vitro binding to human erythrocyte carbonic anhydrase was determined by fluorescence competition assay employing the fluorescent CA inhibitor dans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.780nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human carbonic anhydrase 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant full length CA7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human full length carbonic anhydrase 7 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of full length human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi: <1nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi: <1nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  5.40nMAssay Description:Mean inhibitory constant towards human carbonic anhydrase II determined by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibition of human cloned cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against human carbonic anhydrase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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