BDBM107120 US8592415, 4

SMILES Clc1ccc(cc1)N1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1

InChI Key InChIKey=FNIUNMYSUAZBAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 107120   

TargetTyrosine-protein kinase JAK3(Human)
Reaction Biology

US Patent
LigandPNGBDBM107120(US8592415, 4)
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Reaction Biology

US Patent
LigandPNGBDBM107120(US8592415, 4)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Reaction Biology

US Patent
LigandPNGBDBM107120(US8592415, 4)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Reaction Biology

US Patent
LigandPNGBDBM107120(US8592415, 4)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent