BDBM105225 US8580800, 1

SMILES CN1CC2=C([C@H](NC(=O)N2c3cccc(c3)C(F)(F)F)c4ccc(cc4)C#N)C(=O)N1

InChI Key InChIKey=UPNMBPLODWPJQQ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105225   

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM105225(US8580800, 1)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)