BDBM10504 1-[3-({[(4-amino-5-fluoro-2-methylquinolin-3-yl)methyl]sulfanyl}methyl)phenyl]-2,2,2-trifluoroethane-1,1-diol::4-Amino-5-fluoro-2-methyl-3-[3-(1,1-dihyroxy-2,2,2-trifluoroethyl)-benzylthiomethyl]quinoline::Aminoquinoline 28

SMILES Cc1c(c(c2c(n1)cccc2F)N)CSCc3cccc(c3)C(C(F)(F)F)(O)O

InChI Key InChIKey=GPBGHVRNVGXPNM-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10504   

TargetAcetylcholinesterase(Pacific electric ray)
Syngenta

LigandPNGBDBM10504(1-[3-({[(4-amino-5-fluoro-2-methylquinolin-3-yl)me...)
Affinity DataIC50: 1.10E+4nMpH: 7.8 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)