BDBM104913 CHEMBL523865::US8569313, Inhibitor 25

SMILES CCOC(=O)N1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key InChIKey=PNBWWTOCZSBDGF-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 104913   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  65nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  65nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  1.34E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed