BDBM104021 MK408

SMILES c1cc(c(cc1Cl)OCC(=O)O)C(=O)NCc2c(cc(cc2F)Br)F

InChI Key InChIKey=ITCYRGAOHOZIOB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104021   

TargetAldo-keto reductase family 1 member B1(Human)
Academy of Sciences of The Czech Republic

LigandPNGBDBM104021(MK408)
Affinity DataIC50: 1.19E+3nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)