BDBM103364 US8552202, Compound 13

SMILES Cl[C@H]1CN([C@H]2[C@@H]1OCC2=O)C(=O)[C@@H](NC(=O)c1cccc(c1)-n1ccnc1)C1CCCCC1

InChI Key InChIKey=JPQIXMPQVCDFBY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 103364   

TargetCathepsin S(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103364(US8552202, Compound 13)
Affinity DataKi:  1.70nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetCathepsin K(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103364(US8552202, Compound 13)
Affinity DataKi:  23nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetCathepsin L2(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103364(US8552202, Compound 13)
Affinity DataKi:  170nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetProcathepsin L(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103364(US8552202, Compound 13)
Affinity DataKi:  270nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetCathepsin B(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103364(US8552202, Compound 13)
Affinity DataKi:  440nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent