BDBM103349 US8552202, Compound 1

SMILES O=C(N[C@@H](C1CCCCC1)C(=O)N1CC[C@H]2OCC(=O)[C@@H]12)c1ccccc1

InChI Key InChIKey=JHKBBDALNAZURK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 103349   

TargetCathepsin S(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103349(US8552202, Compound 1)
Affinity DataKi:  225nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetCathepsin K(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103349(US8552202, Compound 1)
Affinity DataKi:  305nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetProcathepsin L(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103349(US8552202, Compound 1)
Affinity DataKi:  1.25E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetCathepsin L2(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103349(US8552202, Compound 1)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetCathepsin B(Human)
Amura Therapeutics

US Patent
LigandPNGBDBM103349(US8552202, Compound 1)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent