BDBM10284 4-Oxo-4-piperidin-1-yl-N-(1,3,4-trioxo-1,2,3,4-tetrahydro-isoquinolin-6-yl)-butyramide::4-oxo-4-(piperidin-1-yl)-N-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanamide::Isoquinoline-1,3,4-trione 13c

SMILES O=C(CCC(=O)N1CCCCC1)Nc1ccc2C(=O)NC(=O)C(=O)c2c1

InChI Key InChIKey=OZAFISSWLZQMIS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 10284   

TargetCaspase-3(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10284(4-oxo-4-(piperidin-1-yl)-N-(1,3,4-trioxo-1,2,3,4-t...)
Affinity DataIC50: 25nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed
TargetCaspase-2(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10284(4-oxo-4-(piperidin-1-yl)-N-(1,3,4-trioxo-1,2,3,4-t...)
Affinity DataIC50: 231nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed
TargetCaspase-6(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10284(4-oxo-4-(piperidin-1-yl)-N-(1,3,4-trioxo-1,2,3,4-t...)
Affinity DataIC50: 124nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed
TargetCaspase-7(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10284(4-oxo-4-(piperidin-1-yl)-N-(1,3,4-trioxo-1,2,3,4-t...)
Affinity DataIC50: 64nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed
TargetCaspase-8(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10284(4-oxo-4-(piperidin-1-yl)-N-(1,3,4-trioxo-1,2,3,4-t...)
Affinity DataIC50: 288nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed