BDBM100714 US8507676, 63::US9062045, Comparator No. 2

SMILES CN1CCN(CC1)c1cnc2ccc(Cc3nnc4ccc(nn34)C(\C)=N\OCCO)cc2c1

InChI Key InChIKey=YFCXQUJKPIVRBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 100714   

TargetHepatocyte growth factor receptor(Human)
Novartis

US Patent
LigandPNGBDBM100714(US8507676, 63 | US9062045, Comparator No. 2)
Affinity DataIC50: 6nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2013
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Novartis

US Patent
LigandPNGBDBM100714(US8507676, 63 | US9062045, Comparator No. 2)
Affinity DataIC50: 6nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent

LigandPNGBDBM100714(US8507676, 63 | US9062045, Comparator No. 2)
Affinity DataIC50: 4.00E+3nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent