BDBM10004 1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)methyl]-1H-1,2,4-triazole::1-[(6-Methoxybenzofuran-2-yl)-(4-fluorophenyl)methyl]-1H-1,2,4-triazole::Benzofuran Triazole Derivative 7a

SMILES COc1ccc2cc(oc2c1)C(c1ccc(F)cc1)n1cncn1

InChI Key InChIKey=OIGKCDATUYCETC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10004   

TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed