BDBM50329105 19(S)-Heyneanine::CHEMBL463317::voacristine

SMILES COC(=O)[C@@]12C[C@@H]3C[C@H]([C@H](C)O)[C@@H]1N(C3)CCc1c2[nH]c2ccc(OC)cc12

InChI Key InChIKey=OYMQKBZMKFJPMH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329105   

LigandPNGBDBM50329105(19(S)-Heyneanine | voacristine | CHEMBL463317)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx HEK cells assessed as increase in intracellular Ca2+ accumulation by Fluo-4 AM dye based fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50329105(19(S)-Heyneanine | voacristine | CHEMBL463317)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at mouse TRPM8 expressed in T-REx HEK cells assessed as increase in intracellular Ca2+ accumulation by Fluo-4 AM dye based fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50329105(19(S)-Heyneanine | voacristine | CHEMBL463317)
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity against human TRPV1 expressed in T-REx HEK cells assessed as inhibition of capsaicin-induced increase in intracellular Ca2+ accum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50329105(19(S)-Heyneanine | voacristine | CHEMBL463317)
Affinity DataIC50: 4.20E+5nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed