BDBM50325674 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one::CHEMBL226034::Tamarixetin (22)::tamarixetin

SMILES COc1ccc(cc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O

InChI Key InChIKey=FPLMIPQZHHQWHN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50325674   

TargetAurora kinase B(Human)
Konkuk University

LigandPNGBDBM50325674(3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-...)
Affinity DataIC50: 7.39E+3nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2015
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325674(3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325674(3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325674(3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50325674(3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-...)
Affinity DataIC50: 9.37E+4nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50325674(3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed